Research reports on fibromyalgia from E. Alentorngeli and colleagues provide new insights.

Biotech Week.  July 8, 2009 p1188.

According to a study from Barcelona, Spain, “The purpose of this study was to investigate the effect of acute and chronic wholebody vibration exercise on serum insulin-like growth factor-1 (IGF-1) levels in women with fibromyalgia. A randomized controlled two-factor mixed experimental design was used.”

“Twenty-four women with fibromyalgia (age +/- standard error of the mean, 54.95 +/- 2.03) were randomized into the vibration group or the control group. The vibration group underwent a protocol of static and dynamic tasks with wholebody vibration exercise twice a week for a total of six weeks, whereas the control group performed the same protocol without vibratory stimulus. Both groups continued their usual pharmacological treatment. Serum IGF-1 levels were determined using enzyme-linked immunosorbent assay (ELISA). To test the effects of long-term wholebody vibration exercise, serum IGF-1 measurements were taken at baseline and at weeks 1, 3, and 6 of the intervention. To test the short-term effects, at week 1, serum IGF-1 measurements were taken before and immediately following a session of wholebody vibration exercise. Treatment adherence was 93% in the vibration group and 92% in the control group. None of the subjects dropped out of the study. There was an absence of change in IGF-1 at week 1 and week 6 of wholebody vibration exercise. Results show no change in serum IGF-1 levels in women with fibromyalgia undergoing wholebody vibration exercise,” wrote E. Alentorngeli and colleagues (see also Fibromyalgia).

The researchers concluded: “Although high-intensity exercise and wholebody vibration exercise have been shown to increase serum IGF-1 in healthy individuals, the effectiveness of wholebody vibration exercise as a strategy to produce improvements in serum IGF-1 levels in women with fibromyalgia could not be demonstrated.”

Alentorngeli and colleagues published their study in the Journal of Alternative and Complementary Medicine (Effect of Acute and Chronic WholeBody Vibration Exercise on Serum Insulin-Like Growth Factor-1 Levels in Women with Fibromyalgia. Journal of Alternative and Complementary Medicine, 2009;15(5):573-578).

For more information, contact G. Moras, INEFC Barcelona, Av Estadi S-N Anella Olimpica, Barcelona 08038, Spain.

Publisher contact information for the Journal of Alternative and Complementary Medicine is: Mary Ann Liebert Inc., 140 Huguenot Street, 3RD FL, New Rochelle, NY 10801, USA.

Keywords: Spain, Barcelona, Clinical Trial Research, Complementary Medicine, Experimental Design, Fibromyalgia, Fibromyalgia Syndrome, Pharmaceuticals, Pharmacological.

This article was prepared by Biotech Week editors from staff and other reports. Copyright 2009, Biotech Week via

Record Number: A203683968
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